mandom corp.

Research & Development

Unique Initiatives that Maximize
Our Dedication to Service (Oyakudachi)

Commitment to Functionality & Comfort

Mandom's efforts in product development seek to prioritize safety first, and find an optimal balance between functionality and comfort.

Example 1

TRP Channel Research

In 2007, Mandom was the first company in the cosmetics industry to develop a method for evaluating unpleasant sensory irritation on the skin, such as stinging or burning sensations, using irritant receptors known as "TRP (Transient Receptor Potential) channels." The company is continuing its search for mechanisms that trigger sensory irritation and components that reduce that irritation, and applies that technology to developing women's cosmetics, hair coloring products, and deodorants.

Related release

Mandom and the National Institutes of Biomedical Innovation, Health and Nutrition confirmed for the first time in Japan that TRPM4, a cell sensor, controls inflammatory reactions in keratinocytes

Mandom received Hiroshi and Aya Irisawa Memorial Award for Excellent Papers in The Journal of Physiological Sciences at The 96th Annual Meeting of Physiological Society of Japan

Mandom received Paper Award at the 94th Annual Meeting of the Physiological Society of Japan

Mandom identified menthol-induced analgesic mechanisms.

Identification by Mandom of the mechanism by which hypo-osmotic solutions such as water cause irritation in the nasal cavity and eyes

Identification of a mechanism by Mandom to perceive cold temperature as cold change

Role of the eucalyptus-derived ingredient eucalyptol in reducing unpleasant sensory irritation from cooling sensations - Investigations by Mandom

Mandom identifies the relationship between sensory irritation and irritant receptors in the skin-First time in the cosmetics industry

Evaluation of sensory irritation using irritant receptors: novel method development in the cosmetics industry by Mandom to develop gentler skin products

Example 2

Finding a Balance Between Increased Hair Dye Functionality & Reduced Irritation in Hair Dye Products

Mandom was the first company in the world to discover that the mechanism which causes irritation and discomfort when using hair dye products is caused by alkaline components that enhance hair dye functions. The company also applied this research to discover that carbonate ions are effective at reducing sensory irritation. As a result, Mandom was able to develop hair dye products that have both increased hair dye functionality and reduced irritation to the skin.

Related release

Discovery of reduced hair coloring sensory irritation using carbonate ions by Mandom

Sensory Irritation During Use of Hair Color Products: "Can This Unpleasant Feeling be Reduced?"

Example 3

Foam Face Wash

Mandom utilized its expert knowledge to successfully develop an exquisitely resilient foam face wash with fine and consistent bubbles. The foam easily adheres to uneven skin surfaces, and the fine bubbles reach deep into pores to remove dirt. The foam also has rubber-like properties that allow it to clean dirt by simply being moved across the skin's surface, which in turn reduces friction and burden to the skin.